Mediation of the influence of childhood maltreatment on depression relapse by cortical structure: a 2-year longitudinal observational study.

Mediation of the influence of childhood maltreatment on depression relapse by cortical structure.
They link childhood abuse with changes in the brain and subsequent depression.

Early life stress has a detrimental effect on brain structure, which increases the risk of unfavourable disease courses in major depression. Clinical and translational research should explore the role of childhood maltreatment as causing a potential clinically and biologically distinct subtype of major depressive disorder.

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(19)30044-6/fulltext

https://www.neurologia.com//noticia/7180/vinculan-el-abuso-infantil-con-cambios-en-el-cerebro-y-depresion-posterior