* Post-traumatic stress disorder (PTSD)

Exposure to stress has been causally linked to changes in hippocampal volume (HV). Given that the hippocampus undergoes rapid changes in the first years of life, stressful experiences during this period may be particularly important in understanding individual differences in the development of the hippocampus. “This work underscores the plasticity and vulnerability of the brain in early life,”Humphreys said. “Our findings have important clinical implications given that smaller hippocampal volume has been prospectively linked to a number of outcomes, including vulnerability to psychopathology following trauma, poorer antidepressant treatment response and memory deficits.”

https://www.ncbi.nlm.nih.gov/pubmed/30471167

https://news.vanderbilt.edu/2018/12/19/stress-and-trauma-in-earliest-years-linked-to-reduced-hippocampal-volume-in-adolescence/

https://www.diariodasaude.com.br/news.php?article=trauma-infancia-afeta-cerebro-mesmo-quando-nao-lembramos&id=13244&nl=sit

https://onlinelibrary.wiley.com/doi/abs/10.1111/desc.12775?af=R