Autism spectrum disorder is a neurodevelopmental disorder characterised by an atypical brain structure from the first months of gestation. These structural differences may be the consequence of heterochrony in the divisions of the periventricular germ cells. Whether due to a too rapid growth of developing cells (proliferation), a defect in neuronal migration, or a failure to eliminate leftover neurons (apoptosis), the result is an increase in short-range neuronal connections and an decrease in the long-range. The functional anomalies that this entails could explain most of the cognitive and behavioural manifestations of the people who suffer from it. The aim of this work is to integrate and synthesise the latest advances in the study of neuronal connections that could be involved in these manifestations.
https://psiquiatria.com/neuropsiquiatria/conexion-neuronal-en-el-trastorno-del-espectro-autista/