Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling.

In the current study, we demonstrate that oral treatment with selective serotonin reuptake inhibitors (SSRI) leads to modulation of vagus nerve activity and that intact vagal signaling between the gut and brain is required to mediate the behavioral effects of these drugs in the tail suspension test (TST), a commonly used screen for potential antidepressants.… Continuar lendo Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling.

Depression: When It’s More Than a Symptom Of ADHD: Distinguishing Between Depression and ADHD.

To most people, depression means feeling blue or down in the dumps. This is an almost universal experience for people with ADHD. At some point in their lives, they feel down due to the frustration and demoralization of trying to fit into a neurotypical world that makes little effort to understand or accept them. Often this is called… Continuar lendo Depression: When It’s More Than a Symptom Of ADHD: Distinguishing Between Depression and ADHD.

Emotionality and temperament in attention deficit disorder with or without hyperactivity.

Those who suffer from attention deficit disorder with or without hyperactivity (ADHD) find it difficult to direct their emotions in order to solve challenges or problems. This alteration in emotional self-regulation implies greater disability than that attributed to the traditional dimensions -attention deficit and hyperactivity- with an evident impact on the development of personality. The… Continuar lendo Emotionality and temperament in attention deficit disorder with or without hyperactivity.