Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios.

Bumetanide has been reported to alter synaptic excitation–inhibition (E-I) balance by potentiating the action of γ-aminobutyric acid (GABA), thereby attenuating the severity of autism spectrum disorder (ASD) in animal models. However, clinical evidence of its efficacy in young patients with ASD is limited. This was investigated in the present clinical trial of 83 patients, randomised… Continuar lendo Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios.

Child-Centered Play Therapy as a Means of Healing Children Exposed to Domestic Violence.

  Increasingly, domestic violence is being recognized as a major concern for children today. Hamby, Finkelhor, Turner, and Ormrod (2011) of the U.S. Department of Justice discovered that approximately 8.2 million children were exposed to some form of family violence in the past year and 18.8 million over their lifetime as reported by a national survey. Witnessing physical as… Continuar lendo Child-Centered Play Therapy as a Means of Healing Children Exposed to Domestic Violence.

Artificial Intelligence Boosts MRI Detection of ADHD.

Deep learning can boost the power of MRI in predicting attention deficit hyperactivity disorder (ADHD), according to a study published in Radiology: Artificial Intelligence. Increasingly, the connectome is regarded as key to understanding brain disorders like ADHD. According to the National Survey of Children’s Health, approximately 9.4% of U.S. children, ages 2 to 17 years (6.1… Continuar lendo Artificial Intelligence Boosts MRI Detection of ADHD.