Psychosocial Interventions for Attention-Deficit/Hyperactivity Disorder: Systematic Review with Evidence and Gap Maps.

Objective: To inform the scope of future systematic reviews, meta-analyses, and treatment outcome studies, this review aims to describe the extent of the evidence for psychosocial interventions for children and adolescents with attention-deficit/hyperactivity disorder, with particular attention to specific types of interventions, targets of outcome assessment, and risk of bias. Method: A comprehensive search of relevant databases… Continuar lendo Psychosocial Interventions for Attention-Deficit/Hyperactivity Disorder: Systematic Review with Evidence and Gap Maps.

“I’m Smart, So I Should Be Able to Overpower ADHD. Right?”

High-IQ adults with ADHD seem to function well, but it comes at a high emotional cost. They feel burdened and exhausted, blaming their struggles on themselves, not on their ADHD. Here is a game plan for healing and hope. DHD is distributed across individuals of all intellectual levels, and some of those individuals have high… Continuar lendo “I’m Smart, So I Should Be Able to Overpower ADHD. Right?”

Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.

Mutations that inactivate negative translation regulators cause autism spectrum disorders (ASD), which predominantly affect males and exhibit social interaction and communication deficits and repetitive behaviors. However, the cells that cause ASD through elevated protein synthesis resulting from these mutations remain unknown. Here we employ conditional overexpression of translation initiation factor eIF4E to increase protein synthesis… Continuar lendo Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.