Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice.

Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically developing (TD) and ASD individuals, though it remains unclear whether the microbiome contributes to symptoms. We transplanted gut microbiota from human donors with ASD or TD controls into… Continuar lendo Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice.

Neuronal connection in autism spectrum disorder.

Autism spectrum disorder is a neurodevelopmental disorder characterised by an atypical brain structure from the first months of gestation. These structural differences may be the consequence of heterochrony in the divisions of the periventricular germ cells. Whether due to a too rapid growth of developing cells (proliferation), a defect in neuronal migration, or a failure… Continuar lendo Neuronal connection in autism spectrum disorder.

Boston Autism Consortium Searches for Genetic Clues to Autism’s Puzzle.

Autism has received considerable attention in the past few years; some say its incidence is increasing. Upon closer examination, however, the picture blurs. A nascent initiative in Boston, the Boston Autism Consortium, may represent a pragmatic model for dealing with complex diseases, one that involves different institutions collaborating rather than competing and applying research directly… Continuar lendo Boston Autism Consortium Searches for Genetic Clues to Autism’s Puzzle.