Association of Genetic and Environmental Risks for Attention-Deficit/Hyperactivity Disorder With Hypomanic Symptoms in Youths.

outubro 28, 2019

Attention-deficit/hyperactivity disorder and hypomanic symptoms appear to be associated with similar genetic factors.

More than a quarter of the genetic risk factors for adolescent hypomanic traits were also associated with ADHD symptoms in childhood and adolescence, with hypomania-specific genetic risk factors detected. These findings suggest that ADHD and hypomanic symptoms are associated with shared genetic factors, which should be the focus of further research.

**Path Diagram for Cholesky Decomposition**The pathways from the latent variables (enclosed in circles) labeled A1, A2, and A4 to the 2 hypomania scales estimate the proportion of variation in hypomania that is associated with genetic risk factors for attention-deficit/hyperactivity disorder (ADHD) traits at 9, 12, 15, and 18 years of age. The pathway from A3 to hypomania at 15 years of age represents the proportion of genetic variance in hypomania at 15 years of age that is independent of ADHD traits. Hypomania at 18 years of age was associated with genetic risk factors for ADHD traits at each age (A1, A2, and A4), genetic risk factors for hypomania at 15 years of age (A3), and genetic factors that are unique to hypomania at 18 years of age (A5). Equivalent pathways are included for C, D, and E.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694400/

https://psiquiatria.com/trastornos-infantiles-y-de-la-adolescencia/asociacion-de-riesgos-geneticos-y-ambientales-para-el-tdah-con-sintomas-hipomaniacos-en-jovenes/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694400/

https://psiquiatria.com/trastornos-infantiles-y-de-la-adolescencia/asociacion-de-riesgos-geneticos-y-ambientales-para-el-tdah-con-sintomas-hipomaniacos-en-jovenes/

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